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25 Postdoctoral Position at Fred Hutchinson Cancer Research Center, USA

25 Postdoctoral Position at Fred Hutchinson Cancer Research

Center, USA

 

Fred Hutchinson Cancer Research Center, USA invites online Application for various Postdoctoral Position. We are providing a list of Postdoc positions available at Fred Hutchinson Cancer Research Center, USA.

Eligible candidate may Apply as soon as possible.

 

(01) Postdoctoral Position

Postdoctoral position summary/title: Research Fellow, Biostatistics.

Responsibilities include the development and dissemination of statistical methodology, software development, and application to large-scale genetic epidemiological studies. Specific areas of interest include multiclass regression model, nonparametric modeling and methods, multiple hypothesis testing, machine learning, and genome-wide risk modeling. The fellow will have real-hand data analysis experience by participating in large collaborative studies, in which rich data on tumor genomics, germline genetics and environmental risk factors have been collected.

Deadline of Postdoc Position: Open Until Filled

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(02) Postdoctoral Position

Postdoctoral position summary/title:  Research Fellow, Bioengineering.

The Postdoctoral Fellow recruited for this position will study the protective immune responses in human barrier tissue, such as skin and mucosa, against viral pathogens, including human herpes simplex virus. The candidate will participate in research activities:

to expand the development of three-dimensional (3-D) ‘tissue organoids’ and/or ‘organ-on-chip’ platforms based on our new ‘skin-on-chip’ microfluidic device incorporated with a microvascular network, and
to delineate viral-host interactions and understand monocytes, neutrophils and lymphocytes recruitment and function in human tissues using our in vitro tissue model system.
to evaluate newly discovered antiviral drugs and compounds.

Deadline of Postdoc Position: Open Until Filled

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(03) Postdoctoral Position

Postdoctoral position summary/title: A postdoctoral position is immediately available in the Geballe Lab at the Fred Hutchinson Cancer Research Center. The Geballe Laboratory studies the roles, mechanisms and evolution of antagonism of host cell defenses during infections by large DNA viruses, especially herpesviruses and and vaccinia virus. Additional project focus on control of gene expression at the translational level.

Deadline of Postdoc Position: Open Until Filled

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(04) Postdoctoral Position

Postdoctoral position summary/title: Research Fellow, Bioengineering.

The Postdoctoral Fellow recruited for this position will study the protective immune responses in human barrier tissue, such as skin and mucosa, against viral pathogens, including human herpes simplex virus. The candidate will participate in research activities:

  1. to expand the development of three-dimensional (3-D) ‘tissue organoids’ and/or ‘organ-on-chip’ platforms based on our new ‘skin-on-chip’ microfluidic device incorporated with a microvascular network, and
  2. to delineate viral-host interactions and understand monocytes, neutrophils and lymphocytes recruitment and function in human tissues using our in vitro tissue model system.
  3. to evaluate newly discovered antiviral drugs and compounds.

Deadline of Postdoc Position: Open Until Filled

View details

 

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(05) Postdoctoral Position

Postdoctoral position summary/title: Research Fellow, Biostatistics

Responsibilities include the development and dissemination of statistical methodology, software development, and application to large-scale genetic epidemiological studies. Specific areas of interest include multiclass regression model, nonparametric modeling and methods, multiple hypothesis testing, machine learning, and genome-wide risk modeling. The fellow will have real-hand data analysis experience by participating in large collaborative studies, in which rich data on tumor genomics, germline genetics and environmental risk factors have been collected.

Deadline of Postdoc Position: Open Until Filled

View details

 

(06) Postdoctoral Position

Postdoctoral position summary/title: Research Fellow, Innate Immunity to HIV-1.

A Post-Doctoral Research Fellow position is available with Dr. Anthony Rongvaux, Ph.D. at Fred Hutchinson Cancer Research Center. The Rongvaux Lab uses state of the art humanized murine models to study innate immune responses specific to the human species. This research project focuses on the fundamental mechanisms of innate immunity to HIV-1 infection.

Deadline of Postdoc Position: Open Until Filled

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(07) Postdoctoral Position

Postdoctoral position summary/title: Research Fellow, T Cell Immunotherapy – Chapuis Lab.

The post-doctoral research fellow will work on independent and collaborative projects in Dr. Chapuis’ laboratory developing adoptive T cell immunotherapy within the Program in Immunology and Clinical Research Division at Fred Hutchinson Cancer Research Center. This highly translational research will involve the development of novel TCR-based cellular therapies for clinical translation; development of next-generation humanized murine models to gain insights into the in vivo barriers to effective therapy; and may include monitoring patients through-out the course of treatment with T cell therapies.  Additionally, the successful applicant will employ strategies for improving current immunotherapy treatments, including and not limited to; cloning and characterizing T cell receptors (TCRs) specific for cancer-associated antigens, developing cutting-edge strategies for genetic modification of human T cells including CRISPR-based gene editing, and developing/testing new approaches for overcoming immunosuppressive signals in the tumor microenvironment.

Deadline of Postdoc Position: Open Until Filled

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(08) Postdoctoral Position

Postdoctoral position summary/title: Research Fellow, Cell Biology.

A postdoctoral position for a recent enthusiastic PhD graduate is available in a lab in the Basic Sciences Division to study the nuclear envelope budding or mechanisms of single cell wound healing in the Drosophila model system. The candidate will carry out independent research projects related to these topics. The candidate will also participate in lab meetings and journal clubs, and contribute to the smooth running of the lab.

Deadline of Postdoc Position: Open Until Filled

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(09) Postdoctoral Position

Postdoctoral position summary/title: Research Fellow- Stamatatos Lab.

We have two positions for Postdoctoral fellows interested in: 1) Investigating the development of B cell and antibody responses against SARS-CoV-2 in adult and pediatric patients and 2) Investigating the activation and expansion of B cells that produce HIV-1 neutralizing antibodies in immunized humanize murine.

Deadline of Postdoc Position: Open Until Filled

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(10) Postdoctoral Position

Postdoctoral position summary/title:  Research Fellow- Stamatatos Lab.

We have two positions for Postdoctoral fellows interested in: 1) Investigating the development of B cell and antibody responses against SARS-CoV-2 in adult and pediatric patients and 2) Investigating the activation and expansion of B cells that produce HIV-1 neutralizing antibodies in immunized humanize murine.

Deadline of Postdoc Position: Open Until Filled

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(11) Postdoctoral Position

Postdoctoral position summary/title: Research Fellow, Viral Immunology.

We have two positions for Postdoctoral fellows interested in:

  • Investigating the development of B cell and antibody responses against SARS-CoV-2 in adult and pediatric patients
  • Investigating the activation and expansion of B cells that produce HIV-1 neutralizing antibodies in immunized humanize murine

Deadline of Postdoc Position: Open Until Filled

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(12) Postdoctoral Position

Postdoctoral position summary/title: Research Fellow – Functional Genomics and RNA Biology.

The goal of this postdoc research project is to use functional genomic approaches to discover and characterize novel mechanisms of mRNA translation in human cells. Our longer-term goal is to identify how these mechanisms are dysregulated across different tissue types and disease states. Thanks to methods such as ribosome profiling and RNA-seq, we have unprecedented genome-wide snapshots of gene expression at single nucleotide resolution. However, our ability to interrogate and predict the functional effects of mRNA sequence motifs on gene expression and cell physiology has been limited. We aim to address this gap using:

  • Pooled deep sequencing methods to measure in parallel the effects of thousands of mRNA sequence motifs on gene expression in human cells.
  • Unbiased CRISPR screens to identify factors that act at specific motifs.
  • Machine learning and kinetic models to quantitatively predict the effect of novel mRNA motifs on gene expression.
  • Biochemical and genetic studies to test the resulting models of gene regulation.

Deadline of Postdoc Position: Open Until Filled

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(13) Postdoctoral Position

Postdoctoral position summary/title: Research Fellow, Grady Lab

A postdoctoral position is available immediately in the Grady lab at Fred Hutch. The applicant will perform data-driven research using state-of-the-art bioinformatics and computational biology tools across various research projects to advance translational research in epi/genomics of gastrointestinal cancers Adherence to principles of reproducible research, motivation to keep up with cutting-edge data analysis tools, and willingness to team-work in multi-disciplinary research programs will be vital to success in this position. The laboratory is situated in the Clinical Research Division at Fred Hutch.

Deadline of Postdoc Position: Open Until Filled

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(14) Postdoctoral Position

Postdoctoral position summary/title: Research Fellow, Grady Lab.

A postdoctoral position is available immediately in the Grady lab at Fred Hutch. The applicant will perform data-driven research using state-of-the-art bioinformatics and computational biology tools across various research projects to advance translational research in epi/genomics of gastrointestinal cancers Adherence to principles of reproducible research, motivation to keep up with cutting-edge data analysis tools, and willingness to team-work in multi-disciplinary research programs will be vital to success in this position. The laboratory is situated in the Clinical Research Division at Fred Hutch.

Deadline of Postdoc Position: Open Until Filled

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(15) Postdoctoral Position

Postdoctoral position summary/title: Research Fellow, Pancreas and Biliary Cancer Pathogenesis.

Successful candidates will learn to generate and exploit a series of cancer model systems including genetically engineered murine models (GEMMs), patient-derived xenografts and novel human cancer cell lines to understand fundamental pathogenic mechanisms underlying pancreatic cancer. To answer these questions the laboratory uses state-of-the-art techniques in murine models and genetics, molecular biology, cell biology, biochemistry, metabolism, RNA profiling, proteomics, pharmacology, genomics and computational biology.

Deadline of Postdoc Position: Open Until Filled

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(16) Postdoctoral Position

Postdoctoral position summary/title: Research Fellow, Pancreas and Biliary Cancer Pathogenesis.

The Kugel Laboratory is seeking a highly motivated postdoctoral fellow interested in exploring how the dysregulation of chromatin modifying enzymes and developmental pathways contribute to pancreas and biliary cancer pathogenesis and, further, whether these pathways present liabilities that can be exploited for cancer therapy

Deadline of Postdoc Position: Open Until Filled

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(17) Postdoctoral Position

Postdoctoral position summary/title: The post-doctoral research fellow will work on projects in the Bleakley Lab primarily on laboratory studies including, but not limited to, cancer antigen discovery, molecular cloning and evaluation of T cell receptors (TCRs) and transgene constructs in vitro and in vivo patient derived-xenograft models, and tracking T cell responses to cancer antigens in patient tissue samples.

Deadline of Postdoc Position: Open Until Filled

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(18) Postdoctoral Position

Postdoctoral position summary/title: Research Fellow, Molecular Neuroscience/Neurodegeneration.

A postdoctoral fellow position in Molecular Neuroscience/Neurodegeneration is available in the Fred Hutch lab of Dr. Linda Buck. Dr. Buck received a Nobel Prize in Physiology or Medicine in 2004 for “Odorant receptors and the organization of the olfactory system”. Current projects in the Buck lab focus on molecular mechanisms that underlie stress, appetite, and neurodegeneration and how they are influenced by the olfactory system. The lab has developed and uses cutting edge technologies to unravel neural mechanisms and neural circuits underlying specific functions/dysfunctions. These include novel genomics methods to define neural circuits, genetic and chemical control of neuronal activation, imaging of gene expression and neuronal activation, gene editing, and single cell genomics.

Deadline of Postdoc Position: Open Until Filled

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(19) Postdoctoral Position

Postdoctoral position summary/title: Research Fellow, Mathematical Modeler.

A Postdoctoral Research Fellow position with focus on development, refinement, and utilization of different classes of epidemiological transmission models, is available in the Vaccine and Infectious Disease Division at the Fred Hutchinson Cancer Research Center. Applicant will be joining a dynamic multi-disciplinary group to work on methods for effective model configuration and calibration using data collected by the COVID-19 Prevention Trials Network (CoVPN) as a basis for the methodological work. Among the key objectives of the modeling work are improving the understanding of SARS-CoV-2 transmission and COVID-19 disease dynamics, informing effective public health strategies, and guiding rational development of new preventive interventions, including vaccination programs. The position will require a substantial amount of programming and computation, good organization and communication skills.

Deadline of Postdoc Position: Open Until Filled

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(20) Postdoctoral Position

Postdoctoral position summary/title: Research Fellow, Computational Cancer Biology.

The laboratory of Dr. Gavin Ha has a Post-Doctoral Research Fellow position open in the Computational Biology Program of the Public Health Sciences and Human Biology Divisions. We are seeking a highly motivated individual who is interested in developing and implementing innovative computational and analytical approaches to study the genetics and epigenetics of cancer. Candidates who are excited about large/complex ‘omics’ data analysis of cancer genomes, computational methods development, and “liquid biopsy” research are encouraged to apply. The position has a competitive salary with great benefits.  
 

Deadline of Postdoc Position: Open Until Filled

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(21) Postdoctoral Position

Postdoctoral position summary/title: Research Fellow, Intratumoral Microbiome Environment.

The Bullman Laboratory in the Human Biology Division at the Fred Hutchinson Cancer Research Center is recruiting a highly motivated Postdoctoral Fellow with expertise in murine models of cancer and mammalian cell biology to join our tumor microbiome efforts. An interest in microbiome research is required but hands on experience is not required as ample training can be provided.

Deadline of Postdoc Position: Open Until Filled

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(22) Postdoctoral Position

Postdoctoral position summary/title: Research Fellow, HIV Vaccine Design & Testing

The McGuire Lab is seeking outstanding postdoctoral fellows to work on a project involving the validating and testing of novel vaccine candidates to elicit broadly neutralizing antibodies against HIV-1.  Responsibilities include: 

  • Design and execute prime-boost immunization regimens in a humanized murine model which will serve as a surrogate for human vaccine trials 
  • Perform endpoint analyses including antigen-specific B cell sorting and serum antibody binding and neutralization assays to gain a high-resolution understanding of the immune response to immunization. 
  • To complement this analysis the candidate will perform single B cell sorting of human PBMC samples ascertain the identity of antigen-reactive naive B cells.  
  • May be required to help with SARS-CoV-2 work as needed 

Deadline of Postdoc Position: Open Until Filled

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(23) Postdoctoral Position

Postdoctoral position summary/title: A fully-funded post-doctoral research fellow position is available in the Hatch Lab in the Basic Sciences Division. We study the structure and dynamics of the mammalian nuclear envelope, and our primary interests are to understand why and how nuclear membranes rupture and repair, and how defects in nuclear membrane stability impact cancer development (Hatch et al., Cell, 2013; Maciejowski and Hatch, Ann Rev Cell Dev Biol, 2020; Young, Gunn, and Hatch, MBoC, 2020). The Hatch lab uses a variety of techniques to achieve these goals with a focus on microscopy and cell-based tool development.

Deadline of Postdoc Position: Open Until Filled

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(24) Postdoctoral Position

Postdoctoral position summary/title: Research Fellow, Protein Therapeutics for Acute Myeloid Leukemia.

The Walter Laboratory in the Clinical Research Division is recruiting an outstanding postdoctoral research fellow to work as part of a team investigating new treatments for patients with acute myeloid leukemia (AML) primarily focused on improving existing, and developing novel, antibody-based immunotherapies, and rendering them safer for clinical application. Current projects include preclinical drug development/testing (in part with academic and industry partners), studies on mechanisms of action and resistance of antibody-based therapeutics and identification of strategies to overcome these limitations, and development of approaches to protect normal tissues from the toxicities of AML-targeted therapies (e.g. via use of genome editing).

Deadline of Postdoc Position: Open Until Filled

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(25) Postdoctoral Position

Postdoctoral position summary/title: Research Fellow, Protein Therapeutics for Acute Myeloid Leukemia.

The Walter Laboratory in the Clinical Research Division is recruiting an outstanding postdoctoral research fellow to work as part of a team investigating new treatments for patients with acute myeloid leukemia (AML) primarily focused on improving existing, and developing novel, antibody-based immunotherapies, and rendering them safer for clinical application. Current projects include preclinical drug development/testing (in part with academic and industry partners), studies on mechanisms of action and resistance of antibody-based therapeutics and identification of strategies to overcome these limitations, and development of approaches to protect normal tissues from the toxicities of AML-targeted therapies (e.g. via use of genome editing).

Deadline of Postdoc Position: Open Until Filled

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About Fred Hutchinson Cancer Research Center

The center grew out of the Pacific Northwest Research Foundation, founded in 1956 by Dr. William B. Hutchinson (1909–1997). The Foundation was dedicated to the study of heart surgery, cancer, and diseases of the endocrine system. Hutchinson’s younger brother Fred (1919–1964), was a major league pitcher and manager who died of lung cancer at age 45. The next year, Dr. Hutchinson established the Fred Hutchinson Cancer Research Center as a division of the Pacific Northwest Research Foundation.

In 1972, with the help of Senator Warren G. Magnuson, PNRF received federal funding under the National Cancer Act of 1971 to create in Seattle one of the 15 new NCI-designated Cancer Centers aimed at conducting basic research called for under 1971 Act; the Fred Hutchinson Cancer Research Center became independent 1972 and its building opened three years later in 1975.

 

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